Treating Kawasaki disease (KD)

Treatment should begin as soon as possible if your child is diagnosed with having Kawasaki disease.

Aspirin and intravenous immunoglobulin are the two main treatment methods used.


Aspirin is a non-steroidal anti-inflammatory drug (NSAID). It is used to treat Kawasaki disease because it helps prevent heart complications:

  • it can ease pain and discomfort
  • it can help reduce a fever
  • helps to reduce swelling (anti-inflammatory) and also helps to prevent blood clots from forming (antiplatelet)

The dose of aspirin that your child is prescribed and how long they need to take it for will depend on their symptoms.  Low dose aspirin may be prescribed six to eight weeks after the acute phase of KD to reduce the risk of blood clots.

Intravenous immunoglobulin

Intravenous immunoglobulin is also called IVIG or gamma globulin. IVIG is purified antibodies taken from blood donors. Antibodies are proteins the immune system produces to fight disease-carrying organisms.  IVIG can reduce fever and the risk of heart problems.

After your child is given IVIG, their symptoms should improve within 36 hours.  If their fever does not improve after 36 hours, they may be given a second dose of IVIG.